Preparation of Antibacterial Microcapsules Loaded with Matrine and the Application to Cotton Fabrics 


Vol. 26,  No. 9, pp. 3777-3788, Sep.  2025
10.1007/s12221-025-01045-5


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  Abstract

Matrine, a natural fungicide derived from legumes, exhibits significant antibacterial and antifungal activities against Escherichia coli, Staphylococcus aureus, and Candida albicans. Matrine-loaded agar microcapsules were synthesized utilizing the emulsification technique. Under conditions where the stirring speed was set at 10,000 rpm, the core-to-wall ratio was maintained at 1:5, and the emulsification temperature was established at 80 °C, the microcapsules exhibited a drug loading efficiency of 15.1% and an encapsulation efficiency of 75.6%. These microcapsules were subsequently affixed to cotton fibers using waterborne polyurethane, resulting in an antibacterial cotton fabric(Matrine@Agar/Cot) capable of inhibiting the proliferation of Escherichia coli, Staphylococcus aureus, and Candida albicans to a significant degree. The warp breaking strength of Matrine@Agar/Cot decreased by 1%, the weft breaking strength decreased by 6.3%, and the air permeability decreased by 5%, while the mechanical strength and air permeability of the fabric remained largely unchanged. The antibacterial rates of Matrine@Agar/Cot against E. coli, S. aureus, and Candida albicans were 73.9%, 72.5%, and 80.0%, respectively. After 10 washing cycles, these rates decreased to 66.7%, 51.6%, and 59.5%, respectively. After 30 and 40 washes, Matrine@Agar/Cot could not produce an inhibitory effect on E.coli, S.aureus, and Candida albicans.

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  Cite this article

[IEEE Style]

C. Li, G. Tong, N. Fang, M. Zhou, B. Xu, Y. Liu, "Preparation of Antibacterial Microcapsules Loaded with Matrine and the Application to Cotton Fabrics," Fibers and Polymers, vol. 26, no. 9, pp. 3777-3788, 2025. DOI: 10.1007/s12221-025-01045-5.

[ACM Style]

Chaojun Li, Guozhu Tong, Ninghao Fang, Man Zhou, Bo Xu, and Ying Liu. 2025. Preparation of Antibacterial Microcapsules Loaded with Matrine and the Application to Cotton Fabrics. Fibers and Polymers, 26, 9, (2025), 3777-3788. DOI: 10.1007/s12221-025-01045-5.