A pH-Responsive Textile Functionalized with a Luteolin-Cyclodextrin Polymer Complex 


Vol. 27,  No. 4, pp. 1689-1702, Apr.  2026
10.1007/s12221-026-01316-9


PDF
  Abstract

To develop a pH-responsive drug-releasing textile, a water-soluble cyclodextrin polymer (HCP) was synthesized and loaded with luteolin (Lut) to form an inclusion complex. This complex was immobilized onto cationized cotton via electrostatic adsorption and subsequent Ca2⁺ cross-linking. The resulting textile achieved a stable drug loading of 0.106 mg/cm2 while exhibiting high tensile strength (467.5 N) and good water vapor permeability (1100 g/m2). In vitro release studies demonstrated a pH-responsive mechanism with accelerated release in the acidic microenvironment (pH 5.5) compared to physiological pH 7.4. The functionalized textile displayed bacteriostatic activity against S. aureus and biocompatibility with L929 fibroblasts. Kinetic analysis indicated a diffusion-controlled release profile fitted to the Higuchi model, suggesting potential for smart wound-dressing applications.

  Statistics
Cumulative Counts from November, 2022
Multiple requests among the same browser session are counted as one view. If you mouse over a chart, the values of data points will be shown.


  Cite this article

[IEEE Style]

X. Sun, W. Chen, M. Wang, "A pH-Responsive Textile Functionalized with a Luteolin-Cyclodextrin Polymer Complex," Fibers and Polymers, vol. 27, no. 4, pp. 1689-1702, 2026. DOI: 10.1007/s12221-026-01316-9.

[ACM Style]

Xiao-Zhu Sun, Wan-Chang Chen, and Meng Wang. 2026. A pH-Responsive Textile Functionalized with a Luteolin-Cyclodextrin Polymer Complex. Fibers and Polymers, 27, 4, (2026), 1689-1702. DOI: 10.1007/s12221-026-01316-9.