Antimicrobial, Antibiofilm and Cytotoxicity Activity of a New Acridine Hyperbranched Polymer in Solution and on Cotton Fabric 


Vol. 20,  No. 1, pp. 19-24, Jan.  2019
10.1007/s12221-019-8687-4


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  Abstract

For the first time a fluorescent hyperbranched polymer modified with acridine (P1000-Acrid) was tested in vitro for antimicrobial activity against different model pathogens. The results showed strong activity of the compound against the used Gram-positive and Gram negative bacteria and yeasts. Cytotoxicity effect of P1000-Acrid has been studied towards HEp-2 cell line. The antibacterial finishing of cotton fabric treated with the P1000-Acrid was evaluated towards Grampositive and Gram-negative bacteria. It has been shown that the studied P1000-Acrid polymer reduces bacterial growth and prevents the formation of biofilm. The obtained results indicate that the studied P1000-Acrid hyperbranched polymer possess good antimicrobial potential with the greatest effectiveness against the used Gram-positive strains.

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  Cite this article

[IEEE Style]

E. Vasileva-Tonkova, D. Staneva, S. Medel, P. Bosch, P. Grozdanov, I. Nikolova, I. Grabchev, "Antimicrobial, Antibiofilm and Cytotoxicity Activity of a New Acridine Hyperbranched Polymer in Solution and on Cotton Fabric," Fibers and Polymers, vol. 20, no. 1, pp. 19-24, 2019. DOI: 10.1007/s12221-019-8687-4.

[ACM Style]

Evgenia Vasileva-Tonkova, Desislava Staneva, Sandra Medel, Paula Bosch, Petar Grozdanov, Ivanka Nikolova, and Ivo Grabchev. 2019. Antimicrobial, Antibiofilm and Cytotoxicity Activity of a New Acridine Hyperbranched Polymer in Solution and on Cotton Fabric. Fibers and Polymers, 20, 1, (2019), 19-24. DOI: 10.1007/s12221-019-8687-4.

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pISSN : 1229 - 9197
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