Fabrication and Characterization of Electrospun Scaffold Based on Polycaprolactone-Aloe vera and Polyvinyl Alcohol for Skin Tissue Engineering 


Vol. 21,  No. 8, pp. 1694-1703, Aug.  2020
10.1007/s12221-020-9922-8


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  Abstract

In the present work, the biodegradable nanofibrous scaffolds containing poly(caprolactone) (PCL), poly(vinyl alcohol) (PVA) and aloe vera (AV), through two nozzles electrospinning method, were prepared and characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, contact angle measurement and mechanical analysis. The biocompatibility and cell growth were evaluated using MTT (3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide) assay. Adding poly(vinyl alcohol) (PVA) and poly(caprolactone) (PCL) boosted the electrospinability of aloe vera (AV) solution and mechanical features of the scaffolds. According to the Scanning electron microscopy (SEM) results, uniform PVA/AV-PCL nanofibers were fabricated with the average diameter about 119

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  Cite this article

[IEEE Style]

M. Shabannejad, M. S. Nourbakhsh, A. Salati, Z. Bahrami, "Fabrication and Characterization of Electrospun Scaffold Based on Polycaprolactone-Aloe vera and Polyvinyl Alcohol for Skin Tissue Engineering," Fibers and Polymers, vol. 21, no. 8, pp. 1694-1703, 2020. DOI: 10.1007/s12221-020-9922-8.

[ACM Style]

Marjan Shabannejad, Mohammad Sadegh Nourbakhsh, Amir Salati, and Zohreh Bahrami. 2020. Fabrication and Characterization of Electrospun Scaffold Based on Polycaprolactone-Aloe vera and Polyvinyl Alcohol for Skin Tissue Engineering. Fibers and Polymers, 21, 8, (2020), 1694-1703. DOI: 10.1007/s12221-020-9922-8.

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