Cytocompatible Xanthan Gum/N-halamine and Chitosan Blending Film with Efficient Antibacterial and Hemostatic Properties 


Vol. 24,  No. 3, pp. 845-854, Mar.  2023
10.1007/s12221-023-00120-z


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  Abstract

An ideal biomedical material should possess several characteristics like good cytocompatibility, appropriate mechanical properties, and high biocidal and hemostatic effi ciency. To achieve the goal, in this study, a kind of antibacterial blend fi lm (XG/CEDMH-Cl&CS) was prepared by N-halamine-modifi ed-xanthan gum (XG/CEDMH-Cl) and chitosan (CS). This fi lm presented good antibacterial performance and no zone of inhibition, thus indicating that this blend fi lm belonged to non-dissolving bactericidal materials. The blood clotting index (BCI) value and the cytotoxicity toward NIH-3T3 fi broblast cells were also studied, and the results displayed that XG/CEDMH-Cl&CS fi lm was satisfactory. In addition, the appropriate water vapor transmission rate, mechanical property and swelling property demonstrated that this fi lm can be served as a wound dressing material and might have great prospects in the fi eld of biomedical materials.

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  Cite this article

[IEEE Style]

Y. Liu, J. Zhang, T. Zhong, X. Ren, "Cytocompatible Xanthan Gum/N-halamine and Chitosan Blending Film with Efficient Antibacterial and Hemostatic Properties," Fibers and Polymers, vol. 24, no. 3, pp. 845-854, 2023. DOI: 10.1007/s12221-023-00120-z.

[ACM Style]

Ying Liu, Jianxun Zhang, Tian Zhong, and Xuehong Ren. 2023. Cytocompatible Xanthan Gum/N-halamine and Chitosan Blending Film with Efficient Antibacterial and Hemostatic Properties. Fibers and Polymers, 24, 3, (2023), 845-854. DOI: 10.1007/s12221-023-00120-z.

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