HEMA/PU Structures for Intraocular Lens Applications 


Vol. 62,  No. 5, pp. 291-296, Oct.  2025
10.12772/TSE.2025.62.291


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  Abstract

Posterior capsular opacification (PCO) is a common complication after cataract surgery caused by the proliferation of residual lens epithelial cells. This study aimed to develop intraocular lenses (IOLs) with reduced PCO incidence by optimizing material composition and surface properties. Hydrophilic poly(2-hydroxyethyl methacrylate) (HEMA) was crosslinked with poly(ethylene glycol) diacrylate (PEGDA), and its thermal and optical properties were evaluated. The incorporation of PEGDA enhanced crystallinity and mechanical stability, particularly when a 15-minute solvent evaporation step was applied before curing. Furthermore, surface modification with a polyurethane (PU) coating increased hydrophobicity, which is expected to contribute to the suppression of PCO. The PU coating also preserved high optical transparency of over 90% at wavelengths above 400 nm and ensured appropriate stiffness, facilitating surgical handling. These results demonstrate that PEGDA crosslinking combined with PU surface coating improves the thermal stability, transparency, and mechanical integrity of the fabricated lenses. The approach applied in this study provides a practical framework for material design in intraocular lenses aimed at reducing posterior capsular opacification.

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  Cite this article

[IEEE Style]

한주연, 손예진, 김주현, 서원, 송영석, "HEMA/PU Structures for Intraocular Lens Applications," Textile Science and Engineering, vol. 62, no. 5, pp. 291-296, 2025. DOI: 10.12772/TSE.2025.62.291.

[ACM Style]

한주연, 손예진, 김주현, 서원, and 송영석. 2025. HEMA/PU Structures for Intraocular Lens Applications. Textile Science and Engineering, 62, 5, (2025), 291-296. DOI: 10.12772/TSE.2025.62.291.

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pISSN : 1225 - 1089
eISSN : 2288 - 6419

한국연구재단 우수등재학술지 유지 (2022년)