Physical and Biological Properties of Bio-membranes Obtained by Using PVA and Sulfonated Polymers 


Vol. 55,  No. 4, pp. 286-294, Aug.  2018
10.12772/TSE.2018.55.286


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  Abstract

We prepared bio-membranes by mixing polyvinyl alcohol (PVA) with a natural polymer [κ-Carrageenan (κ-Car) or chondroitin sulfate (CS)] having a sulfonate group similar to proteoglycan of articular cartilage and investigated the mechanical, thermal, and surface properties of these bio-membranes that varied with the content ratio of the natural polymer. We found that the mechanical properties of the bio-membranes decreased with the ratio of κ-Car or CS. It was found that the mesenchymal stem cells (MSCs) virtually did not adhere to the PVA hydrogel film prepared by freeze-thawing method, whereas they adhered to the PVA hydrogel film prepared by solution casting. In addition, the adhesion rate of the MSCs on the bio-membranes gradually increased with the ratio of κ-Car or CS.

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pISSN : 1225 - 1089
eISSN : 2288 - 6419

한국연구재단 우수등재학술지 유지 (2022년)