Crosslinking Effects and Mechanical Properties of Glutaraldehyde Crosslinked Wet-Spun Collagen Fibers

Collagen is a natural protein with excellent biocompatibility. Purified collagen is used in various medical and cosmetic products. Fibers made from collagen are particularly used for medical purposes, but their mechanical properties are not good; therefore, manufacturing processes such as crosslinking and blending are being researched and developed to reinforce fibers and improve fiber spinnability. Particularly, in the crosslinking process, fiber properties can be manipulated and adjusted based on the crosslinking agent. In this study, the spinnability and mechanical properties of the fibers were analyzed according to the crosslinking concentration and crosslinking process time. Through this, the crosslinked collagen spinning conditions that can achieve a sufficient crosslinking effect with a minimum concentration and process time were examined. The processing efficiency and mechanical properties of the collagen fibers were improved by optimizing the crosslinking conditions.

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Crosslinking Effects and Mechanical Properties of Glutaraldehyde Crosslinked Wet-Spun Collagen Fibers

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