Influence of Reduced Graphene Oxide@Titanium Dioxide on the Physical and Biological Features of Electrospun Silk Fibroin Mats 


Vol. 26,  No. 7, pp. 2803-2815, Jul.  2025
10.1007/s12221-025-01018-8


PDF
  Abstract

During the repair of bone defects, the clinical application of biomaterial-based scaffolds is limited by their insufficient mechanical strength and the lack of antibacterial properties. In this study, a reduced graphene oxide (rGO)@titanium dioxide (TiO2) composite was synthesized using a hydrothermal method. Subsequently, rGO@TiO2 was utilized as a reinforcement material to prepare regenerated silk fibroin (RSF)/rGO@TiO2 electrospun composite fibrous mats with enhanced mechanical properties, antibacterial properties, and good biocompatibility. The results indicated that TiO2 nanoparticles were successfully grown on the surface of rGO through covalent bonding (C-O-Ti). Once the content of rGO@TiO2 nanoparticles increased, the average fibrous diameter, β-sheet content, crystallinity, crystallite size, and hydrophilicity of the composite mats gradually decreased. The composite mat prepared using a rGO@TiO2:RSF mass ratio of 1.3:100 exhibited a maximum tensile strength of 1.15±0.06 MPa, representing a 150% increase compared to the pure RSF mat. Under the same conditions, rGO@TiO2 enhanced the antibacterial properties of RSF mats against Escherichia coli and Staphylococcus aureus compared to single GO or TiO2. Furthermore, the RSF/rGO@TiO2 mat exhibited excellent biocompatibility, promoting the spreading, adhesion, and proliferation of MC3T3-E1 cells.

  Statistics
Cumulative Counts from November, 2022
Multiple requests among the same browser session are counted as one view. If you mouse over a chart, the values of data points will be shown.


  Cite this article

[IEEE Style]

C. Zhang, Z. Zhou, X. Wang, J. Sun, J. Liu, Y. Liu, Y. Li, W. Ye, "Influence of Reduced Graphene Oxide@Titanium Dioxide on the Physical and Biological Features of Electrospun Silk Fibroin Mats," Fibers and Polymers, vol. 26, no. 7, pp. 2803-2815, 2025. DOI: 10.1007/s12221-025-01018-8.

[ACM Style]

Chao Zhang, Zhicheng Zhou, Xinru Wang, Jing Sun, Jingjing Liu, Yong Liu, Ying Li, and Wei Ye. 2025. Influence of Reduced Graphene Oxide@Titanium Dioxide on the Physical and Biological Features of Electrospun Silk Fibroin Mats. Fibers and Polymers, 26, 7, (2025), 2803-2815. DOI: 10.1007/s12221-025-01018-8.

Search
(IN TITLE, AUTHOR, ABSTRACT,KEYWORDS)

Advanced Search ▼

POPULAR KEYWORDS
(TOP 10 KEYWORDS)

Recent Publications
(LAST 3 YEARS)

pISSN : 1229 - 9197
eISSN : 1875 - 0052

Impact Factor(2024): 2.3