Manufacturing and Optimization the Nanofibres Tissue of Poly(Nvinyl-2-pyrrolidone) - Poly(e-caprolactone) Shell/Poly(N-vinyl-2-pyrrolidone) -Amphotericin B Core for Controlled Drug Release System 


Vol. 19,  No. 3, pp. 620-626, Mar.  2018
10.1007/s12221-018-7496-x


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  Abstract

ntly by increasing working distance. Moreover, the stress and strain were increased by increasing working distance. Coaxial nanofibers biodegradability rate and drug release of nanofibers were increased also by increasing working distance and flow rate of core. Nanofibers drug release mechanism was indicated by Korsmeyer-Peppas which they followed fick쾠 lows and Higuchi model significantly. Also, results presented that biodegradability and drug release rate accelerate with increasing the working distance and increasing the amount of PVP in core.

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  Cite this article

[IEEE Style]

F. R. V. a. D. Semnani, "Manufacturing and Optimization the Nanofibres Tissue of Poly(Nvinyl-2-pyrrolidone) - Poly(e-caprolactone) Shell/Poly(N-vinyl-2-pyrrolidone) -Amphotericin B Core for Controlled Drug Release System," Fibers and Polymers, vol. 19, no. 3, pp. 620-626, 2018. DOI: 10.1007/s12221-018-7496-x.

[ACM Style]

Fataneh Rouhollahi Vernosfaderani and Dariush Semnani. 2018. Manufacturing and Optimization the Nanofibres Tissue of Poly(Nvinyl-2-pyrrolidone) - Poly(e-caprolactone) Shell/Poly(N-vinyl-2-pyrrolidone) -Amphotericin B Core for Controlled Drug Release System. Fibers and Polymers, 19, 3, (2018), 620-626. DOI: 10.1007/s12221-018-7496-x.