Expanding Application of Immobilized Candida Antarctica Lipase B: A Green Enzyme Catalyst for Knoevenagel Condensation Reaction 


Vol. 19,  No. 8, pp. 1611-1617, Aug.  2018
10.1007/s12221-018-8200-5


PDF
  Abstract

We propose a green synthesis of benzopyran compound based on immobilized lipase. Firstly, by using a combined electrospun membrane and biocompatible chitosan, we show that the chitosan-functionalized electrospun PMA-co-PAA fibrous membrane can provide effective anchoring sites for immobilization of the Candida antarctica lipase B (CALB), and a maximum loading amount of CALB (152 mg/g) can be achieved. Then, the resulting membrane displays enhanced stability in catalyzing Knoevenagel condensation reaction of salicylaldehyde with active methylene compound in mixed aqueousorganic media. The catalytic activity and stability of the CALB on chitosan-modified fiber is better than its non-immobilized counterpart. Furthermore, this immobilize CALB catalyst still retained about 45 % of the initial activity after 5 cycles, which potentially had implications for the design of 쐅reen enzyme catalyst for sustainable organic synthesis.

  Statistics
Cumulative Counts from November, 2022
Multiple requests among the same browser session are counted as one view. If you mouse over a chart, the values of data points will be shown.


  Cite this article

[IEEE Style]

C. Wang, N. Wang, X. Liu, P. Wan, X. He, Y. Shang, "Expanding Application of Immobilized Candida Antarctica Lipase B: A Green Enzyme Catalyst for Knoevenagel Condensation Reaction," Fibers and Polymers, vol. 19, no. 8, pp. 1611-1617, 2018. DOI: 10.1007/s12221-018-8200-5.

[ACM Style]

Cuie Wang, Ning Wang, Xinhua Liu, Peng Wan, Xinwei He, and Yongjia Shang. 2018. Expanding Application of Immobilized Candida Antarctica Lipase B: A Green Enzyme Catalyst for Knoevenagel Condensation Reaction. Fibers and Polymers, 19, 8, (2018), 1611-1617. DOI: 10.1007/s12221-018-8200-5.

Search
(IN TITLE, AUTHOR, ABSTRACT,KEYWORDS)

Advanced Search ▼

POPULAR KEYWORDS
(TOP 10 KEYWORDS)

Recent Publications
(LAST 3 YEARS)

pISSN : 1229 - 9197
eISSN : 1875 - 0052

Impact Factor(2022): 2.5