Transdermal Delivery of Crocin Using Bacterial Nanocellulose Membrane 


Vol. 20,  No. 10, pp. 2025-2031, Oct.  2019
10.1007/s12221-019-9076-8


PDF
  Abstract

This work reports the inclusion of crocin (an active agent of saffron) into bacterial nanocellulose (BNC) membrane for transdermal drug delivery. The BNC showed good uptake of the crocin based on the swelling studies and vibrational peaks of the FTIR spectra. Surface morphology of the crocin loaded BNC showed that the fibrous nano feature was still intact with no fiber damages. The crocin release via direct dissolution showed typical burst release. Franz diffusion test revealed stable and prolong drug permeation. Partition coefficient of the BNC-crocin via mice epidermal skin diffusion was found to be 2.44

  Statistics
Cumulative Counts from November, 2022
Multiple requests among the same browser session are counted as one view. If you mouse over a chart, the values of data points will be shown.


  Cite this article

[IEEE Style]

M. Abba, Z. Ibrahim, C. S. Chong, N. A. Zawawi, M. R. A. Kadir, A. H. M. Yusof, S. I. A. Razak, "Transdermal Delivery of Crocin Using Bacterial Nanocellulose Membrane," Fibers and Polymers, vol. 20, no. 10, pp. 2025-2031, 2019. DOI: 10.1007/s12221-019-9076-8.

[ACM Style]

Mustapha Abba, Zaharah Ibrahim, Chun Shiong Chong, Nurliyana Ahmad Zawawi, Mohammed Rafiq Abdul Kadir, Abdul Halim Mohd Yusof, and Saiful Izwan Abd Razak. 2019. Transdermal Delivery of Crocin Using Bacterial Nanocellulose Membrane. Fibers and Polymers, 20, 10, (2019), 2025-2031. DOI: 10.1007/s12221-019-9076-8.