Fabrication of Gehlenite Nanopowder Containing Electrospun Nanofibers for Bone Tissue Engineering 


Vol. 22,  No. 12, pp. 3281-3288, Dec.  2021
10.1007/s12221-021-0168-x


  Abstract

Bioactive Polycaprolactone/Collagen nanofibers containing gehlenite Nano-powder were fabricated using electrospinning for bone tissue engineering. The physicochemical properties of scaffolds measured using scanning electron microscopy, tensile test, FTIR spectroscopy, and water contact angle measurement test. A slight enhancement (~20 nm) in fibers diameter was observed by adding gehlenite nanoparticles to the scaffolds, but the fiber diameter distributions for both scaffolds were within the normal range of extracellular matrix (50-500 nm). In vitro experiments demonstrated well attachment and higher proliferation of MG-63 cells on gehlenite nanoparticles containing scaffolds. Besides, the stimulatory cell differentiation effects of Polycaprolactone/Collagen/gehlenite scaffolds were demonstrated by Alizarin red staining. This study represents for advanced of the natural and synthetic polymers for bone tissue engineering.

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  Cite this article

[IEEE Style]

M. Doostmohammadi, M. Mehrasa, A. Bigham, M. Rafienia, S. Amini, Z. Komeily-Nia, P. Heidarian, B. Nasri-Nasrabadi, "Fabrication of Gehlenite Nanopowder Containing Electrospun Nanofibers for Bone Tissue Engineering," Fibers and Polymers, vol. 22, no. 12, pp. 3281-3288, 2021. DOI: 10.1007/s12221-021-0168-x.

[ACM Style]

Mohsen Doostmohammadi, Mohammad Mehrasa, Ashkan Bigham, Mohammad Rafienia, Shahram Amini, Zahra Komeily-Nia, Pejman Heidarian, and Bijan Nasri-Nasrabadi. 2021. Fabrication of Gehlenite Nanopowder Containing Electrospun Nanofibers for Bone Tissue Engineering. Fibers and Polymers, 22, 12, (2021), 3281-3288. DOI: 10.1007/s12221-021-0168-x.

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pISSN : 1229 - 9197
eISSN : 1875 - 0052

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