Study on Antifouling and Blood Compatibility Properties of Carboxyl and Sulfonic Acid Groups Modified Polyvinylidene Fluoride Membrane 


Vol. 24,  No. 3, pp. 801-810, Mar.  2023
10.1007/s12221-023-00062-6


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  Abstract

In this study, a highly effi cient, convenient, and universal protocol of in situ cross-linking copolymerization of 2-hydroxyethyl methacrylate and sodium p-styrenesulfonate in polyvinylidene fl uoride (PVDF) solution was presented to prepare bloodcontacting material with good blood compatibility. The modifi ed PVDF membranes were prepared by liquid뱇iquid-phase inversion technology, which could induce the enrichment of hydrophilic groups including sulfonic acid and hydroxyl groups on the surface of the modifi ed PVDF membranes. The hydrophobic-fl uorinated PVDF surfaces with hydrophilic sulphonic acid and hydroxyl groups exhibited high performance with prolonged clotting time (activated partial thromboplastin time and thrombin time) and low activation of blood components (platelets, coagulation cascade, and complements) when they contacted blood. On the other hand, the ultrafi ltration experiment results revealed the improvement in the antifouling properties of the modifi ed PVDF membranes after the introduction of hydrophilic groups on the membranes surface. The results indicate that the blood-compatible PVDF membranes may have potential to be used in the fi eld of blood purifi cation, and can be used as long-term blood-contacting materials as well.

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  Cite this article

[IEEE Style]

Y. Wang, H. Qin, S. Chen, Y. Liu, J. Luo, S. Nie, "Study on Antifouling and Blood Compatibility Properties of Carboxyl and Sulfonic Acid Groups Modified Polyvinylidene Fluoride Membrane," Fibers and Polymers, vol. 24, no. 3, pp. 801-810, 2023. DOI: 10.1007/s12221-023-00062-6.

[ACM Style]

Yi Wang, Hui Qin, Shuyi Chen, Yuan Liu, Jun Luo, and Shengqiang Nie. 2023. Study on Antifouling and Blood Compatibility Properties of Carboxyl and Sulfonic Acid Groups Modified Polyvinylidene Fluoride Membrane. Fibers and Polymers, 24, 3, (2023), 801-810. DOI: 10.1007/s12221-023-00062-6.

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pISSN : 1229 - 9197
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