Exploring the Role of Ag Nanoparticle Distribution in Novel pH-Sensitive Nanofibers Containing Hyaluronic Acid for Enhanced Wound Healing with Sustained Curcumin Release 


Vol. 25,  No. 4, pp. 1163-1176, Apr.  2024
10.1007/s12221-024-00509-4


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  Abstract

The use of nanofiber patches has received considerable attention as a promising solution for overcoming challenges in drug delivery. In this study, silver nanoparticles (Ag NPs) were incorporated in chitosan (CS), hyaluronic acid (HYA), and polyvinyl alcohol (PVA) to form nanofibers (namely, the CS/HYA/PVA-Ag nanofiber) for the controllable release of curcumin (CUR). The CUR release from the CS/HYA/PVA-Ag nanofibers consistently happened sustainably. Therefore, the prepared CS/HYA/PVA-Ag nanofibers show great promise in terms of their ability to expand the field of pH-dependent transdermal drug delivery (TDD) and sustainably release drugs. Additionally, the scratch assay results of these nanofibers further support their potential applications in wound healing.

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  Cite this article

[IEEE Style]

Z. Sayyar and M. K. Sadigh, "Exploring the Role of Ag Nanoparticle Distribution in Novel pH-Sensitive Nanofibers Containing Hyaluronic Acid for Enhanced Wound Healing with Sustained Curcumin Release," Fibers and Polymers, vol. 25, no. 4, pp. 1163-1176, 2024. DOI: 10.1007/s12221-024-00509-4.

[ACM Style]

Zahra Sayyar and Mahsa Khadem Sadigh. 2024. Exploring the Role of Ag Nanoparticle Distribution in Novel pH-Sensitive Nanofibers Containing Hyaluronic Acid for Enhanced Wound Healing with Sustained Curcumin Release. Fibers and Polymers, 25, 4, (2024), 1163-1176. DOI: 10.1007/s12221-024-00509-4.

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pISSN : 1229 - 9197
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