Preparation and Characterization of Sophora Japonica L Extracts Loaded Polyvinyl Alcohol Nanofibers
Vol. 63, No. 1, pp. 51-62,
Feb. 2026
10.12772/TSE.2026.63.051
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Abstract
Electrospun nanofibers are promising materials for biomedical and cosmetic applications owing to their high porosity, large surface area, and effective moisture control. In this study, polyvinyl alcohol (PVA) nanofibers loaded with Sophora Japonica L. extracts were fabricated by electrospinning, and their structural, antioxidant, and antibacterial properties were evaluated. Extracts from Sophorae flos and Sophorae fructus were prepared using water and 60% ethanol, and their antioxidant activities were assessed by total polyphenol and flavonoid contents as well as DPPH and ABTS radical scavenging assays. The antioxidant activity varied depending on the plant part and extraction solvent, with Sophorae flos ethanol extracts showing the highest activity. PVA nanofibers containing different extract concentrations were successfully fabricated, and uniform fiber morphology was obtained at optimal loading levels. FT-IR and DSC analyses revealed physical interactions and hydrogen bonding between PVA and the extracts, accompanied by reduced crystallinity at higher extract contents. The antioxidant activity of the extracts was retained after incorporation into the nanofibers, with ABTS radical scavenging activity approaching complete scavenging over time. In addition, the extract-loaded PVA nanofibers exhibited antibacterial activity against Escherichia coli and Staphylococcus aureus. These results suggest that Sophora Japonica L. extract-loaded PVA nanofibers have strong potential as biofunctional materials for wound dressings and skincare applications.
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