Preparation of Fish-skin-based Conjugated Collagen Fibers and Nonwovens for Wound Dressings

Collagen is used in various medical and cosmetic materials as a biopolymer. In order to use it for high-end medical fibers, its mechanical properties must be improved, and this can be achieved by conjugating it with fish-skin-based collagen and chitosan. The conjugated collagen fibers can utilize the advantages of the materials and can be applied to make wet-laid nonwovens for wound dressing. In this study, the conjugated collagen fibers were prepared by wet spinning and their surface, optical, and mechanical properties were analyzed based on the various compositions of collagen and chitosan. In addition, the wet-laid nonwovens were manufactured with bilayers, designed with an inner layer of conjugated collagen fibers and an outer layer of cotton/chitosan spunlace nonwoven. The characteristics of the wet-laid nonwovens in terms of their liquid-handling properties and the distribution of their pore sizes were investigated. The results thus obtained show that the use of conjugated fibers in wet-laid nonwovens can affect their properties, which can be controlled by adjusting the composition ratio.

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Preparation of Fish-skin-based Conjugated Collagen Fibers and Nonwovens for Wound Dressings

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