Manufacturing and Separation Characteristics Evaluation of Hemodialysis Membrane Using NIPS 


Vol. 60,  No. 3, pp. 187-193, Jun.  2023
10.12772/TSE.2023.60.187


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  Abstract

Hemodialysis is one of the most common kidney replacement methods such as kidney transplantation and peritoneal dialysis for patients with kidney disease such as renal failure. In this study, a polymer solution containing polyethersulfone(PES) as the main raw material and polyvinylpyrrolidone(PVP), a hydrophilic polymer, was prepared by using different types of non-solvent when manufacturing hemodialysis membranes using the nonsolvent induced phase separation(NIPS) method. The characteristics of the manufactured hemodialysis membrane were analyzed through ATR-FTIR and SEM, and the separation charateristics of the hemodialysis membrane were evaluated by performing simulated dialysis using artificial blood and dialysate. As a result, the chemical structure of the manufactured hemodialysis membranes did not change depending on the type of non-solvent, and in the case of the cross-sectional structure, a finger-like structure and a sponge structure were confirmed according to the non-solvent. The maximum removal rate of toxic materials were Urea 56.97% and Creatinine 52.71%, and protein loss was less than 6%. In addition, cell viability was evaluated as up to 92.4%. The biocompatibility and functionality of the hemodialysis membrane made of PES were confirmed.

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  Cite this article

[IEEE Style]

G. T. Lee, D. C. Oh, Y. K. Hong, "Manufacturing and Separation Characteristics Evaluation of Hemodialysis Membrane Using NIPS," Textile Science and Engineering, vol. 60, no. 3, pp. 187-193, 2023. DOI: 10.12772/TSE.2023.60.187.

[ACM Style]

Gyeong Tae Lee, Do Chang Oh, and Young Ki Hong. 2023. Manufacturing and Separation Characteristics Evaluation of Hemodialysis Membrane Using NIPS. Textile Science and Engineering, 60, 3, (2023), 187-193. DOI: 10.12772/TSE.2023.60.187.