Study on Mechanical Properties and Biocompatibility of PVA/CNC Biomaterial Hydrogel 


Vol. 60,  No. 5, pp. 353-360, Oct.  2023
10.12772/TSE.2023.60.353


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  Abstract

In this study, PVA (polyvinyl alcohol) and CNC (cellulose nano-crystal) composite hydrogel was manufactured and the effect of CNC content less than 1 wt% was investigated on the mechanical properties and cell viability. The CNC was utilized to enhance the compressive stress of the PVA hydrogel. We have focused on a low content of CNC less than 1 wt% because CNC is very expensive to use as an additive. The fabrication of PVA/ CNC hydrogels with CNC contents of 0.25, 0.50, and 0.75 wt% was done using solvent casting and freeze-thawing physical cross-linking method. The compressive strength of the PVA/CNC hydrogel with a CNC content of 0.75 wt% was improved up to 95% higher than that of pristine PVA. Furthermore, through MTT and DAPI staining experiments, PVA/CNC hydrogels exhibited no toxicity and good cell viability due to the smooth proliferation of cells.

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  Cite this article

[IEEE Style]

Y. H. Seo, S. M. Zo, S. S. Han, T. H. Oh, "Study on Mechanical Properties and Biocompatibility of PVA/CNC Biomaterial Hydrogel," Textile Science and Engineering, vol. 60, no. 5, pp. 353-360, 2023. DOI: 10.12772/TSE.2023.60.353.

[ACM Style]

Young Ho Seo, Sun Mi Zo, Sung Soo Han, and Tae Hwan Oh. 2023. Study on Mechanical Properties and Biocompatibility of PVA/CNC Biomaterial Hydrogel. Textile Science and Engineering, 60, 5, (2023), 353-360. DOI: 10.12772/TSE.2023.60.353.

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pISSN : 1225 - 1089
eISSN : 2288 - 6419

한국연구재단 우수등재학술지 유지 (2022년)